Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Magnesium (as Magnesium Oxide)
250 mg
60%
Top Medical Research Studies
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More
Most Useful Reviews
9
Improved knee pain
14 people found this helpful
Magnesium is crucial for our health and involved in numerous processes. A lack of magnesium affects well-being. I took Magnesium from Nature Made to help normalise sleep and noted improvements. My knee pain has lessened since I started taking it, and I'm sleeping soundly.
Read More
9
Joint pain relief
The quality is very good. I have experienced reduced joint, bone, and muscle pain, and it has also helped improve my sleep.
Read More
7.5
Knee pain relief
I purchased this vitamin on the recommendation of friends, and after a month, I feel a significant difference in my body. My knee pain has diminished, and my hair is no longer falling out.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
- All Researches
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
We evaluated how effective magnesium, especially when combined with bupivacaine, is for managing knee pain after arthroscopy. Our study looked at data from 78 randomized trials involving 4,425 participants.
It turns out that magnesium with bupivacaine is the top performer in easing pain right after surgery and at the 24-hour mark, outperforming other analgesics like morphine.
However, magnesium alone didn’t show significant pain relief. We found that using this combination does not lead to more side effects, making it a safe choice for recovery.
It turns out that magnesium with bupivacaine is the top performer in easing pain right after surgery and at the 24-hour mark, outperforming other analgesics like morphine.
However, magnesium alone didn’t show significant pain relief. We found that using this combination does not lead to more side effects, making it a safe choice for recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More
9
We looked into how magnesium can help ease knee pain after total knee arthroplasty. In a study of 80 patients, those who received an injection of magnesium sulfate and ropivacaine experienced significantly less pain and needed less morphine compared to those who got a saline injection. This approach not only reduced morphine use in the first 48 hours but also allowed patients to regain movement quicker. Overall, our findings suggest that magnesium may be a beneficial part of pain management in knee surgery.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved knee pain
14 people found this helpful
Magnesium is crucial for our health and involved in numerous processes. A lack of magnesium affects well-being. I took Magnesium from Nature Made to help normalise sleep and noted improvements. My knee pain has lessened since I started taking it, and I'm sleeping soundly.
Read More
9
Joint pain relief
The quality is very good. I have experienced reduced joint, bone, and muscle pain, and it has also helped improve my sleep.
Read More
7.5
Knee pain relief
I purchased this vitamin on the recommendation of friends, and after a month, I feel a significant difference in my body. My knee pain has diminished, and my hair is no longer falling out.
Read More
6
Reduced knee pain
I have taken this for a short time, but I've already noticed a result; I sleep well and no longer experience knee pain. Previously, I would wake at night due to discomfort. Since starting this remedy, my issues have lessened. I will order more.
Read More
Frequently Asked Questions
6
Reduced knee pain
I have taken this for a short time, but I've already noticed a result; I sleep well and no longer experience knee pain. Previously, I would wake at night due to discomfort. Since starting this remedy, my issues have lessened. I will order more.
7.5
Knee pain relief
I purchased this vitamin on the recommendation of friends, and after a month, I feel a significant difference in my body. My knee pain has diminished, and my hair is no longer falling out.
9
Joint pain relief
The quality is very good. I have experienced reduced joint, bone, and muscle pain, and it has also helped improve my sleep.
9
Improved knee pain
14 people found this helpful
Magnesium is crucial for our health and involved in numerous processes. A lack of magnesium affects well-being. I took Magnesium from Nature Made to help normalise sleep and noted improvements. My knee pain has lessened since I started taking it, and I'm sleeping soundly.
8
Magnesium aids post-surgery pain relief
We investigated the impact of magnesium sulphate in pain management for patients after unicompartmental knee arthroplasty (UKA). In a controlled trial, 61 patients received either a modified pain relief cocktail with magnesium or a traditional one.
Results showed that the modified cocktail led to less pain medication use and improved early joint recovery. In other words, magnesium seemed to enhance pain control and recovery without the use of additional drugs.
Results showed that the modified cocktail led to less pain medication use and improved early joint recovery. In other words, magnesium seemed to enhance pain control and recovery without the use of additional drugs.
7
Magnesium aids knee surgery recovery
We investigated how magnesium sulfate influences recovery after knee surgery. In our study, 148 elderly patients undergoing total knee arthroplasty were divided into two groups: one received magnesium sulfate, while the other received a saline solution.
This double-blind setup allowed us to see if magnesium sulfate could enhance recovery quality after surgery. Our findings indicate that magnesium sulfate does help reduce early postoperative pain and improves overall recovery in these patients.
Overall, magnesium sulfate appears beneficial in managing pain during the recovery process.
This double-blind setup allowed us to see if magnesium sulfate could enhance recovery quality after surgery. Our findings indicate that magnesium sulfate does help reduce early postoperative pain and improves overall recovery in these patients.
Overall, magnesium sulfate appears beneficial in managing pain during the recovery process.
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
8
We investigated the effectiveness of an intra-operative injection combining magnesium sulphate and ropivacaine on pain relief after total knee arthroplasty.
Our study involved eighty patients who were divided into two groups. One group received the magnesium and ropivacaine mixture, while the other received a saline control.
The results showed that those receiving the magnesium injection had significantly lower morphine use and better pain scores during the first day after surgery. They also regained mobility quicker than the control group.
Overall, magnesium demonstrated promising benefits for managing post-operative pain.
Our study involved eighty patients who were divided into two groups. One group received the magnesium and ropivacaine mixture, while the other received a saline control.
The results showed that those receiving the magnesium injection had significantly lower morphine use and better pain scores during the first day after surgery. They also regained mobility quicker than the control group.
Overall, magnesium demonstrated promising benefits for managing post-operative pain.
7
Magnesium efficacy in knee pain assessed
We evaluated how magnesium, among other treatments, impacts knee pain after arthroscopic surgery. In our study, 120 patients received either magnesium sulphate, levobupivacaine, lornoxicam, or a placebo.
We found that all treatments provided better pain relief than the placebo. However, magnesium didn’t prove to be the most effective option; lornoxicam was found to be the leader in terms of pain management.
Thus, while magnesium shows promise as a treatment, it may not be the top choice for post-surgery knee pain relief.
We found that all treatments provided better pain relief than the placebo. However, magnesium didn’t prove to be the most effective option; lornoxicam was found to be the leader in terms of pain management.
Thus, while magnesium shows promise as a treatment, it may not be the top choice for post-surgery knee pain relief.
References
- Zhu Y, Shen S, Cui L, Wu L, Zhang B. Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2024;19:764. doi:10.1186/s13018-024-05233-6
- Xu H, Hao C, Wang X, Du J, Zhang T, et al. Effect of Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial. Drug Des Devel Ther. 2024;18:919. doi:10.2147/DDDT.S444896
- Zhao C, Wang L, Chen L, Wang Q, Kang P. Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2023;18:301. doi:10.1186/s13018-023-03790-w
- Wang Q, Zhao C, Hu J, Ma T, Yang J, et al. Efficacy of a Modified Cocktail for Periarticular Local Infiltration Analgesia in Total Knee Arthroplasty: A Prospective, Double-Blinded, Randomized Controlled Trial. J Bone Joint Surg Am. 2023;105:354. doi:10.2106/JBJS.22.00614
- Choi JW, Lahori A, Merlo JA, Gill O, Ghoddoussi F, et al. Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial. Clin J Pain. 2022;38:388. doi:10.1097/AJP.0000000000001036
- He Y, He H, Li X, Lei G, Xie D, et al. Intra-Articular Magnesium Plus Bupivacaine Is the Most Effective and Safe Postoperative Analgesic Option Following Knee Arthroscopy: A Network Meta-analysis. Arthroscopy. 2022;38:2897. doi:10.1016/j.arthro.2022.03.013
- Shi L, Zhu H, Ma J, Shi LL, Gao F, et al. Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2021;16:111. doi:10.1186/s13018-021-02264-1
- Zhao Z, Zhang X, Peng H, Li W, Liu H, et al. Magnesium Sulfate Combined with a Levobupivacaine Periarticular Cocktail for Analgesia in the Early Postoperative Period after Total Knee Arthroplasty. J Knee Surg. 2021;34:1463. doi:10.1055/s-0040-1710364
- Condello V, Filardo G, Madonna V, Andriolo L, Screpis D, et al. Use of a Biomimetic Scaffold for the Treatment of Osteochondral Lesions in Early Osteoarthritis. Biomed Res Int. 2018;2018:7937089. doi:10.1155/2018/7937089
- Shmagel A, Onizuka N, Langsetmo L, Vo T, Foley R, et al. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018;26:651. doi:10.1016/j.joca.2018.02.002
- Shin HJ, Kim EY, Na HS, Kim TK, Kim MH, et al. Magnesium sulphate attenuates acute postoperative pain and increased pain intensity after surgical injury in staged bilateral total knee arthroplasty: a randomized, double-blinded, placebo-controlled trial. Br J Anaesth. 2016;117:497. doi:10.1093/bja/aew227
- Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2012;40:2032.
- Ekmekci P, Bengisun ZK, Akan B, Kazbek BK, Ozkan KS, et al. The effect of magnesium added to levobupivacaine for femoral nerve block on postoperative analgesia in patients undergoing ACL reconstruction. Knee Surg Sports Traumatol Arthrosc. 2013;21:1119. doi:10.1007/s00167-012-2093-4
- Koltka K, Koknel-Talu G, Asik M, Ozyalcin S. Comparison of efficacy of intraarticular application of magnesium, levobupivacaine and lornoxicam with placebo in arthroscopic surgery. Knee Surg Sports Traumatol Arthrosc. 2011;19:1884. doi:10.1007/s00167-011-1497-x
- Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2009;37:1733.
- Farouk S, Aly A. A comparison of intra-articular magnesium and/or morphine with bupivacaine for postoperative analgesia after arthroscopic knee surgery. J Anesth. 2009;23:508. doi:10.1007/s00540-009-0822-8
